Friday, 12 October 2007


It sounds like a rare form of infantile cancer.
Pancreatoblastoma or infantile adenocarcinoma is an unusual non-functional tumor of the pancreas; it is generally encapsulated, presents organoid pattern containing globular structures with elongate cells (squamoid corpuscles) and acinar or ductal cells or both4. It contains both epithelial and mesenchymal elements20. Horie has subclassified them into two groups: ventral type, occurring in the head, and dorsal type occurring in body and tail with relatively immature histology and poor prognosis7.

Pancreatoblastoma is a curable tumor. Examination of serum AFP levels may be useful for diagnosis and to follow the course of the disease. Complete resection is the treatment of choice. However, tumor is often unresectable at diagnosis and preoperative chemotherapy is needed to reduce tumor volume. We suggest a regimen that include cisplatin and doxorubicin. In patients with incompletely resected disease, postoperative radiation may be indicated.
We are looking at class V cancer and there are only four classes. From what we gather is this is a difficult case.

From further reading, this cancer seems to be occur in children even as fetus.

No comments: